Skip to content
  • Home
  • Team
  • Research
    • Overview
    • Section A
    • Section B
    • Section C
    • Section Z
  • Powerful Science
  • Knowledge Transfer
    • Overview
    • News
    • Publications
  • Contact
  • EN
  • DE

Section B

Microenvironmental changes that influence and modulate osteoclast function at a paracrine local level

Such factors include the products of resident cells that are located in the vicinity of osteoclasts, such as fibroblasts, adipocytes and neutrophils/eosinophils, which undergo a functional change during inflammation and thereby influence osteoclasts. This process creates a functional inflammatory niche that instructs osteoclasts and osteoblasts within the microenvironment which influences bone homeostasis.

Projects

B01

Defining the regulation and role of bone marrow adipocytes during inflammatory bone loss

Martina Rauner, MK 3, UKDD, TUD

B02

The impact of neutrophils and neutrophil-derived myeloperoxidase on osteoclasts and inflammatory bone loss

Ulrike Steffen, Med 3, UKER, FAU

B03

Exploring the protective role of eosinophils in bone loss caused by inflammatory arthritis

Darja Andreev, Med 3, UKER, FAU

B04

Histocytometric and molecular assessment of the inflammatory osteoclastogenic niche in situ

Lina Gölz, Orthodontics, UKER, FAU
Stefan Uderhardt, Med 3, UKER, FAU

B05

Arginine supplementation as new therapeutic option against inflammatory bone loss

Aline Bozec, Med 3, UKER, FAU
Ulrike Schleicher, Microbiology, UKER, FAU

B06

Genetically-driven cell-specific activation of glucocorticoids and GR as a therapeutic tool in inflammatory arthritis

Jan Tuckermann, CME, UU
Ulrike Baschant, MK 3, UKDD, TUD

Section A
Section B
Section C
Section Z
Gefördert von
© 2024 Uniklinikum Erlangen
  • Imprint
  • Privacy Policy
to top