Trained immunity in cardiovascular disease
Riksen NP, Netea MG, Ait-Oufella H, Chavakis T, Hajishengallis G.
European Heart Journal. 2025 Dec. doi: 10.1093/eurheartj/ehaf982.
Cardiac macrophages and their functions in homeostasis and injury
Trimaglio G, Mirtschink P, El-Armouche A, Chavakis T.
Atherosclerosis. 2025 Oct. doi: 10.1016/j.atherosclerosis.2025.120480.
Coagulation Matters: ATIII-Enriched Biomolecular Corona Enhances the Hemocompatibility of PEG Nanoparticles
Londhe V, Maitz MF, Chavakis T, Werner C, Weiss ACG, Besford QA.
Loss of myeloperoxidase aggravates skin and joint inflammation in the mannan-induced psoriatic arthritis mouse model
Ringer M, Maccataio A, Zapf R, Gaculenko A, Adam S, Aust O, Loskarn S, Luther J, Aksoy B, Popp V, Weidner D, Eck M, Munoz L, Bozec A, Uderhardt S, Bäuerle T, Schett G, Krönke G, Hüffmeier U, Frey S, Steffen U.
Journal of Leukocyte Biology. 2025 Sep. doi: 10.1093/jleuko/qiaf110.
Trained immunity in chronic inflammatory diseases and cancer
Hajishengallis G, Netea MG, Chavakis T.
Nature Reviews Immunology. 2025 Jul. doi: 10.1038/s41577-025-01132-x.
A multidimensional analysis of temporomandibular joint and ankle joint erosion in inflammatory arthritis
Andreev D, Porschitz P, Weidner D, Song R, Weider M, Schett G, Gölz L, Bozec A.
Frontiers in Immunology. 2025 Jul. doi: 10.3389/fimmu.2025.1560723.
Innate immune training of osteoclastogenesis promotes inflammatory bone loss in mice.
Haacke N, Wang H, Yan S, Barovic M, Li X, Nagai K, Botezatu A, Hatzioannou A, Gercken B, Trimaglio G, Shah AU, Wang J, Ye L, Jaykar MT, Rauner M, Wielockx B, Chung KJ, Netea MG, Kalafati L, Hajishengallis G, Chavakis T.
Developmental Cell. 2025 Jul. doi: 10.1016/j.devcel.2025.02.001.
Validating Centralized Biobanking Workflows for NMR Metabolomics Using the PRIMA Panel
Altmann H, Barovic M, Straßburger K, Tschäpel M, Jonas S, Poitz DM, Belavgeni A, Chavakis T, Mirtschink P, Funk AM.
Analytical Chemistry. 2025 Feb. doi: 10.1021/acs.analchem.4c04938.
Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis
Jia Y, Li R, Li Y, Kachler K, Meng X, Gießl A, Qin Y, Zhang F, Liu N, Andreev D, Schett G, Bozec A.
Bone Research. 2025 Jan. doi:10.1038/s41413-024-00384-y.
RNA-binding proteins hnRNPM and ELAVL1 promote type-I interferon induction downstream of the nucleic acid sensors cGAS and RIG-I
Kirchhoff A, Herzner AM, Urban C, Piras A, Düster R, Mahlberg J, Grünewald A, Schlee-Guimarães TM, Ciupka K, Leka P, Bootz RJ, Wallerath C, Hunkler C, de Regt AK, Kümmerer BM, Christensen MH, Schmidt FI, Lee-Kirsch MA, Günther C, Kato H, Bartok E, Hartmann G, Geyer M, Pichlmair A, Schlee M.
The EMBO Journal. 2025 Feb. doi:10.1038/s44318-024-00331-x.
JAK/STAT inhibition protects glucocorticoid receptor knockout mice from lethal malaria-induced hypoglycemia and hyperinflammation
Prenen F, Vandermosten L, Knoops S, Pollenus E, Possemiers H, Dagneau de Richecour P, Caratti G, Cawthorne C, Vettorazzi S, Cranshoff Y, Schols D, Claes S, Deroose CM, Himmelreich U, Tuckermann J, Van den Steen PE.
EMBO Molecular Medicine. 2025 Aug. doi:10.1038/s44321-025-00264-w.
Absence of microglial activation and maintained hippocampal neurogenesis in a transgenic mouse model of Crohn’s disease
Masanetz RK, Mundlos H, Stolzer I, Winkler J, Günther C, Süß P.
Cells. 2025 Jun. doi:10.3390/cells14110841.
Emerging Roles of Eosinophils in Bone
Andreev D, Porschitz P.
Current Osteoporosis Reports. 2025 Mar. doi.org/10.1007/s11914-025-00913-6.
IgG glycosylation: biomarker, functional modulator, and structural component
Radovani B, Nimmerjahn F.
The Journal of Immunology. 2024 Dec. doi:10.4049/jimmunol.2400447.
Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates bone erosion in arthritis
Kachler K, Andreev D, Thapa S, Royzman D, Gießl A, Karuppusamy S, Llerins Perez M, Liu M, Hofmann J, Gessner A, Meng X, Rauber S, Steinkasserer A, Fromm M, Schett G, Bozec A.
Annals of the Rheumatic Diseases. 2024 Nov. doi: 10.1136/ard-2023-224774.
Immunomodulatory and anti-inflammatory properties of immunoglobulin G antibodies
Hematianlarki M, Nimmerjahn F.
Immunological Reviews. 2024 Nov. doi:10.1111/imr.13404.
Central trained immunity and its impact on chronic inflammatory and autoimmune diseases
Hajishengallis G, Chavakis T.
Journal of Allergy and Clinical Immunology. 2024 Nov. doi: 10.1016/j.jaci.2024.06.005.
Journey through discovery of 75 years glucocorticoids: evolution of our knowledge of glucocorticoid receptor mechanisms in rheumatic diseases
Eiers AK, Vettorazzi S, Tuckermann JP.
Annals of the Rheumatic Diseases. 2024 Nov. doi: 10.1136/ard-2023-225371.
Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via eosinophil peroxidase
Andreev D, Kachler K, Liu M, Chen Z, Krishnacoumar B, Ringer M, Frey S, Krönke G, Voehringer D, Schett G, Bozec A.
Nature Communications. 2024 Feb. doi:10.1038/s41467-024-45261-8.